个人简介

      詹固，博士，特聘副教授，2007-2016年于四川大学华西药学院学习并获得理学博士学位。同年赴美国纽约州立大学进行博士后研究，合作导师为张强教授，研究多肽的选择性化学合成。随后加入日本国立理化学研究所进行博士后研究，师从著名化学家侯召民教授。相关科研成果发表在Chem. Soc. Rev., Angew. Chem. Int. Ed., J. Am. Chem. Soc., Chem. Sci., Acs Catal.等国际顶级学术期刊上，并获得了“2018年日本国立理化学研究所研究奖励奖”、“2019年日本国立理化学研究所理事长感谢状”、“2019年英国皇家化学会OBC壁报奖”等个人奖项。2019年底加入成都中医药大学药学院，目前的主要研究方向为中药相关手性化合物的催化合成、创新药物研发以及不对称催化新方法开发，已获得“四川省千人计划青年项目”、“成都中医药大学引进人才科研启动项目”的资助。

代表性成果

1. Gu Zhan,+ Wei Du,+ and Ying-Chun Chen*, “Switchable Divergent Asymmetric Synthesis via Organocatalysis” Chem. Soc. Rev. 2017, 46, 1675. (中科院JCR一区，影响因子: 42.8)

2. Gu Zhan, Huai-Long Teng, Yong Luo, Shao-Jie Lou, Masayoshi Nishiura, and Zhaomin Hou*, “Enantioselective Construction of Silicon-Stereogenic Silanes by Scandium-Catalyzed Intermolecular Alkene Hydrosilylation” Angew. Chem. Int. Ed. 2018, 57, 12342. (中科院JCR一区，影响因子: 13.0, highlighted by RIKEN Research)

3. Gu Zhan, Ming-Lin Shi, Qing He, Wei-Jia Lin, Qin Ouyang*, and Ying-Chun Chen*, “Catalyst-Controlled Switch in Chemo- and Diastereoselectivities: Annulations of Morita-Baylis-Hillman Carbonates from Isatins” Angew. Chem. Int. Ed. 2016, 55, 2147. (中科院JCR一区，影响因子: 13.0, ESI前1%高被引论文)

4. Xuefeng Cong, Gu Zhan, Zhenbo Mo, Masayoshi Nishiura, Zhaomin Hou*, “Diastereodivergent [3+2] Annulation of Aromatic Aldimines with Alkenes via C-H Activation by Half-Sandwich Rare-Earth Catalysts” Angew. Chem. Int. Ed. 2020, 142, 5531. (中科院JCR一区，影响因子: 14.6)

5. Huai-long Teng, Yuanhong Ma, Gu Zhan, Masayoshi Nishiura, and Zhaomin Hou*, “Asymmetric C(sp)-H Addition of Terminal Alkynes to Cyclopropenes by a Chiral Gadolinium Catalyst” ACS Catal. 2018, 8, 4705. (中科院JCR一区，影响因子: 12.3)

6. Yuanhong Ma, Shao-Jie Lou, Gen Luo*, Yong Luo, Gu Zhan, Masayoshi Nishiura, and Zhaomin Hou*, “B(C6F5)3/Amine-Catalyzed C(sp)-H Silylation of Terminal Alkynes with Hydrosilanes: Combined Experimental and Theoretical Studie” Angew. Chem. Int. Ed. 2018, 57, 15222. (中科院JCR一区，影响因子: 13.0)

7. Gu Zhan, Ming-Lin Shi, Wei-Jia Lin, and Ying-Chun Chen*, “Direct Asymmetric Aza-Vinylogous-Type Michael Additions of Nitrones from Isatins to Nitroalkenes” Chem. Eur. J. 2017, 23, 6286. (中科院JCR二区，影响因子: 5.2)

8. Gu Zhan, Ming-Lin Shi, Qing He, Wei Du, and Ying-Chun Chen*, “[4 + 3] Cycloadditions with Bromo-Substituted Morita-Baylis-Hillman Adducts of Isatins and N-(ortho-Chloromethyl)aryl Amides” Org. Lett. 2015, 17, 4750. (中科院JCR一区，影响因子: 6.5)

9. Gu Zhan, Qing He, Xin Yuan, and Ying-Chun Chen*, “Asymmetric Direct Vinylogous Michael Additions of Allyl Alkyl Ketones to Maleimides through Dienamine Catalysis” Org. Lett. 2014, 16, 6000. (中科院JCR一区，影响因子: 6.5)

10. Rong Zhou, Jiesheng Li, Han Wen Cheo, Rachel Chua, Gu Zhan, Zhaomin Hou, Jie Wu*, “Visible-light-mediated deuteration of silanes with deuterium oxide” Chem. Sci. 2019, 10, 7340. (中科院JCR一区，影响因子: 9.3)